Multiple sequence alignment with hierarchical clustering
نویسندگان
چکیده
منابع مشابه
Multiple sequence alignment with hierarchical clustering.
An algorithm is presented for the multiple alignment of sequences, either proteins or nucleic acids, that is both accurate and easy to use on microcomputers. The approach is based on the conventional dynamic-programming method of pairwise alignment. Initially, a hierarchical clustering of the sequences is performed using the matrix of the pairwise alignment scores. The closest sequences are ali...
متن کاملMultiple Sequence Alignment Multiple Sequence Alignment
An algorithm for progressive multiple alignment of sequences with insertions " , 1. Introduction The problem of sequence alignment is to find the patterns of sequence conservation and similarity between pairs or sets of given sequences. In biological contexts, similarity between biological sequences usually amounts to either functional or structural similarities or divergence from a common ance...
متن کاملSequence Analysis Multiple structural alignment and clustering of RNA sequences
Motivation: An apparent paradox in computational RNA structure prediction is that many methods, in advance, require a multiple alignment of a set of related sequences, when searching for a common structure between them. However, such a multiple alignment is hard to obtain even for few sequences with low sequence similarity without simultaneously folding and aligning them. Furthermore, it is of ...
متن کاملClustering Traces Using Sequence Alignment
Process mining discovers process models from even logs. Logs containing heterogeneous sets of traces can lead to complex process models that try to account for very different behaviour in a single model. Trace clustering identifies homogeneous sets of traces within a heterogeneous log and allows for the discovery of multiple, simpler process models. In this paper, we present a trace clustering ...
متن کاملMultiple sequence alignment.
Multiple sequence alignments are an essential tool for protein structure and function prediction, phylogeny inference and other common tasks in sequence analysis. Recently developed systems have advanced the state of the art with respect to accuracy, ability to scale to thousands of proteins and flexibility in comparing proteins that do not share the same domain architecture. New multiple align...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 1988
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/16.22.10881